protein
16
Proteins validated
4
Binders
Der p 21 is a lipid-binding allergen from house dust mites that provokes strong IgE responses. Its abundance tracks with severe asthma, making Der p 21 useful for diagnostics and next-generation immunotherapy mixes.
20
5
Der p 7 is a house dust mite allergen that binds lipids and drives perennial IgE responses. Monitoring Der p 7 helps pinpoint high-risk patients and refine precision allergen immunotherapy mixes.
833
134
EGFR is a cell-surface receptor that turns growth factor signals into instructions for cells to divide and survive. Extra copies or mutations drive many tumors, so EGFR is a top target for cancer medicines.
other
7
FGFR1 is a receptor tyrosine kinase that reads fibroblast growth factor cues to guide growth, development, and repair. Genetic activation of FGFR1 drives cancers and skeletal disorders, making selective inhibitors and ligand traps essential tools.
8
IFNAR2 is the high-affinity chain of the type I interferon receptor that senses antiviral cytokines. Differences in IFNAR2 levels shape how strongly tissues respond to infection or autoimmunity.
62
51
IL-7Rα is the alpha chain that pairs with the common gamma chain to deliver IL-7 survival cues to lymphocytes. Surface levels of IL-7Rα forecast immune fitness and highlight intervention points in autoimmunity and leukemia.
27
12
MDM2 is an E3 ligase that binds p53 and marks it for degradation to keep stress responses in check. Tumors that overproduce MDM2 silence p53, so inhibitors aim to restore the tumor suppressor.
0
Hendra virus (HeV) and Nipah virus (NiV) are henipaviruses discovered in the mid-to late 1990s that possess a broad host tropism and are known to cause severe and often fatal disease in both humans and animals.
40
31
PD-L1 is an immune checkpoint ligand that binds PD-1 to quiet T-cell signals and cytokine release. Tumors and immune cells boost PD-L1 under stress, so blocking it can restart anti-tumor immunity.
14
spCas9 is a CRISPR nuclease from Streptococcus pyogenes that uses guide RNA to cut DNA next to an NGG motif. Used for research and therapeutic genome editing.
