Nipah Virus Glycoprotein G

Nipah Virus Glycoprotein G is critical for the virus's ability to infect host cells by binding to cellular receptors. It is primarily responsible for the initial attachment of the virus to the host's endothelial and epithelial cells, facilitating entry into the cells. Alterations in the glycoprotein, such as mutations or changes in expression levels, can affect the efficiency of viral entry, impacting the overall virulence and transmission potential of the virus. This glycoprotein is a key factor in the virus's ability to spread within a host and between individuals, contributing to the severity of outbreaks. Researchers and clinicians focus on Glycoprotein G to better understand and control Nipah virus infections. By studying its structure and function, scientists aim to develop targeted interventions, such as neutralizing antibodies and small molecule inhibitors, to block the virus's entry into host cells. Additionally, Glycoprotein G is a promising target for vaccine development, as it plays a crucial role in the immune response modulation. Monitoring its activity and abundance can also provide valuable insights into disease progression and potential therapeutic strategies, making it an important biomarker in the study of Nipah virus pathology.