Molecular Dynamics + RFdiffusion + CARBonAra

We used Molecular Dynamics Simulations to generate an ensemble of configurations of the target protein. We then selected several centroid structures from this ensemble and generated binder backbones against them using RFdiffusion. Lastly, w…

Description

Proteins (10)

TableGrid

Ffernando.meireles

id: golden-ant-pine

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.21

63.52

15.8 kDa

137

id: ivory-goat-clay

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.23

82.52

15.5 kDa

137

id: quick-toad-jade

Binder

Miniprotein

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.17

70.08

8.9 kDa

id: hollow-bat-snow

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.07

72.76

18.0 kDa

155

id: mellow-bison-frost

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.13

83.61

11.1 kDa

id: silver-jaguar-jade

Binder

Miniprotein

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.34

79.66

8.6 kDa

id: gentle-raven-rose

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.33

70.00

21.5 kDa

193

id: dark-jaguar-ember

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.00

53.35

14.4 kDa

132

id: steady-ant-vine

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.01

78.44

22.0 kDa

197

id: silver-panther-ember

Binder

Miniprotein

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.01

82.43

8.4 kDa