Molecular Dynamics + RFdiffusion + CARBonAra

We used Molecular Dynamics Simulations to generate an ensemble of configurations of the target protein. We then selected several centroid structures from this ensemble and generated binder backbones against them using RFdiffusion. Lastly, w…

Description

Proteins (10)

TableGrid

#97

Ffernando.meireles

id: gentle-raven-rose

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

Binding

Medium

3.9e-7 M

True

21.5 kDa

193

id: ivory-goat-clay

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

82.52

True

15.5 kDa

137

id: quick-toad-jade

Binder

Miniprotein

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

69.85

True

8.9 kDa

id: hollow-bat-snow

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

72.76

True

18.0 kDa

155

id: mellow-bison-frost

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

83.61

True

11.1 kDa

id: silver-jaguar-jade

Binder

Miniprotein

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

79.66

True

8.6 kDa

id: dark-jaguar-ember

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

53.35

True

14.4 kDa

132

id: steady-ant-vine

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

78.44

True

22.0 kDa

197

id: golden-ant-pine

Binder

Other

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

None

63.52

True

15.8 kDa

137

id: silver-panther-ember

Binder

Miniprotein

Molecular Dynamics + RFdiffusion + CARBonAra

Target

Nipah Virus Glycoprotein G

0.01

82.43

8.4 kDa