Description
We have screened an extended selection of designs from the original BindCraft1 publication, including binders that were generated as part of the original design campaigns but did not make it to experimental screening. We aimed at characterising a wide and interesting selection of binding modes and folds.
Proteins (96)
id: hollow-wolf-moss
IFNAR2
Strong
1.6e-8 M
True
9.5 kDa
80
id: golden-cobra-iron
IFNAR2
Strong
3.9e-8 M
True
11.1 kDa
92
id: pale-wolf-flint
IFNAR2
Medium
8.7e-8 M
True
11.2 kDa
93
id: lunar-deer-birch
spCas9
Medium
8.2e-8 M
True
16.6 kDa
138
id: silver-heron-cedar
IFNAR2
Medium
8.4e-8 M
True
11.2 kDa
96
id: silent-otter-moss
spCas9
Medium
1.2e-7 M
True
12.8 kDa
108
id: rapid-ibis-ember
spCas9
Medium
1.0e-7 M
True
13.2 kDa
111
id: small-raven-plume
EGFR
Medium
9.8e-8 M
True
16.3 kDa
138
id: wild-owl-crystal
spCas9
Medium
1.7e-7 M
True
15.5 kDa
129
id: brisk-ant-fern
spCas9
Medium
1.7e-7 M
True
15.2 kDa
124
id: deep-ox-opal
spCas9
Medium
2.6e-7 M
True
14.0 kDa
113
id: wild-quail-fern
IFNAR2
Medium
1.8e-7 M
True
8.4 kDa
71
id: dark-eagle-maple
spCas9
Medium
1.9e-7 M
True
17.1 kDa
140
id: strong-deer-fern
spCas9
Medium
1.9e-7 M
True
13.8 kDa
115
id: silver-seal-plume
spCas9
Medium
2.1e-7 M
True
15.3 kDa
131
id: rapid-cat-granite
spCas9
Medium
2.1e-7 M
True
14.6 kDa
122
id: solid-crane-fern
DERF7
Medium
3.7e-7 M
True
14.8 kDa
119
id: small-fox-ruby
spCas9
Medium
2.5e-7 M
True
14.1 kDa
115
id: azure-tiger-clay
EGFR
Medium
3.1e-7 M
True
15.6 kDa
135
id: brisk-jaguar-frost
IFNAR2
Medium
3.3e-7 M
True
12.2 kDa
104
id: strong-deer-flint
spCas9
Medium
3.4e-7 M
True
14.1 kDa
116