Nipah Binder Competition: Main Submissions

Adaptyv Bio/Nipah Binder Competition: Main Submissions

Description

This collection contains proteins from the "designated" submissions in the Nipah protein binder competition. Participants designed over 11,000 proteins across multiple submissions but were required to select one submission as their official entry. This collection includes only those designated competition entries.

Proteins (3749)

TableGrid

#34

NBNick Boyd

id: noble-swan-clay

Binder

Other

Mosaic

Target

Nipah Virus Glycoprotein G

0.92

85.24

23.5 kDa

220

id: azure-tiger-marble

Binder

Peptide

Target

Nipah Virus Glycoprotein G

0.91

65.46

1.3 kDa

id: frozen-bear-flint

Binder

Other

Mosaic

Target

Nipah Virus Glycoprotein G

0.91

81.63

23.1 kDa

220

id: dark-toad-ash

Binder

Peptide

BoltzGen

Target

Nipah Virus Glycoprotein G

0.90

85.19

1.9 kDa

id: pale-crow-pearl

Binder

Miniprotein

Sampling for max ipsae

Target

Nipah Virus Glycoprotein G

0.90

77.28

7.0 kDa

id: deep-wolf-sand

Binder

Peptide

BoltzGen

Target

Nipah Virus Glycoprotein G

0.89

85.87

5.4 kDa

id: bright-zebra-pearl

Binder

Other

Target

Nipah Virus Glycoprotein G

0.89

75.02

26.7 kDa

240

id: deep-cat-maple

Binder

Nanobody

Target

Nipah Virus Glycoprotein G

0.89

74.42

14.6 kDa

130

id: young-quail-clay

Binder

Other

Mosaic

Target

Nipah Virus Glycoprotein G

0.88

83.24

24.2 kDa

220

id: brisk-hawk-oak

Binder

Other

Target

Nipah Virus Glycoprotein G

0.88

75.22

26.4 kDa

239

id: young-ram-cloud

Binder

Other

Target

Nipah Virus Glycoprotein G

0.88

84.87

13.3 kDa

119

id: golden-seal-thorn

Binder

Other

Protein-Hunter

Target

Nipah Virus Glycoprotein G

0.88

87.00

10.6 kDa

101

id: rapid-lynx-bronze

Binder

Other

DSM Synteract

Target

Nipah Virus Glycoprotein G

0.88

76.45

26.5 kDa

240

LC(WLLeonardo Castorina (Wells Wood Lab)

id: wild-dove-rose

Binder

Miniprotein

co-TIMED

Target

Nipah Virus Glycoprotein G

0.88

76.29

9.5 kDa

id: hollow-shark-ruby

Binder

Miniprotein

Sampling for max ipsae

Target

Nipah Virus Glycoprotein G

0.88

88.87

5.7 kDa

id: golden-otter-cypress

Binder

Other

Protein Hunter Boltz

Target

Nipah Virus Glycoprotein G

0.88

89.16

11.4 kDa

112

id: shy-eagle-fern

Binder

Other

Mosaic

Target

Nipah Virus Glycoprotein G

0.88

86.85

22.8 kDa

220

id: green-lynx-leaf

Binder

Other

DSM Synteract

Target

Nipah Virus Glycoprotein G

0.88

81.00

26.7 kDa

242

id: radiant-quail-cypress

Binder

Miniprotein

PDL1 Prot42 v3 DIPS ipSAE

Target

Nipah Virus Glycoprotein G

0.88

81.19

5.8 kDa

id: lunar-fox-opal

Binder

Miniprotein

RFdiffsion_hth+dl_binder_design+RLpep

Target

Nipah Virus Glycoprotein G

0.88

62.06

3.5 kDa

id: soft-cobra-wave

Binder

Other

Target

Nipah Virus Glycoprotein G

0.87

72.73

26.6 kDa

239

About

3749proteins designed

1028proteins validated

98binders

85%expression rate

Design Methods

ABdesign-a-protein.com595 MIBoltzGen288 EBindCraft100 BLRFdiffusion60 MProt4241 SPXDesign Server30 GLDSM Synteract30 YPrometheus27 LHSynthyra Protein Design Environment20

+178 others

Targets

Nipah Virus Glycoprotein G

98 binders•5.8e-8 avg KD

Design Class

other 45%

miniprotein 21%

peptide 14%

nanobody 13%

scFv 5%

unknown <1%

affibody <1%

Binding Strength

unknown 72%

none 25%

strong 2%

medium 1%

weak <1%

Expressed

unknown 73%

true 23%

false 4%

Classification

mainly Alpha 36%

mainly Beta 30%

alpha Beta 25%

unknown 7%

few Secondary Structures 2%

Architecture

unknown 83%

sandwich 7%

up Down Bundle 3%

orthogonal Bundle 1%

3 Layer Aba Sandwich 1%

alpha Horseshoe <1%

2 Layer Sandwich <1%

roll <1%

alpha Beta Complex <1%

7 Propeller <1%

single Sheet <1%

beta Barrel <1%

helix Non Globular <1%

6 Propeller <1%

alpha Beta Barrel <1%

alpha Beta Horseshoe <1%

other Non Globular <1%

ribbon <1%

3 Layer Bba Sandwich <1%

4 Layer Sandwich <1%

8 Propeller <1%

distorted Sandwich <1%

irregular <1%