Description
The Gleghorn Lab and Synthyra have teamed up to design high affinity binders for BenchBB targets. This is round 1 of binder testing for EGFR and PD-L1) using the DSM model for generation and Synteract models for scoring.
The Gleghorn Lab and Synthyra have teamed up to design high affinity binders for BenchBB targets. This is round 1 of binder testing for EGFR and PD-L1) using the DSM model for generation and Synteract models for scoring.
id: solid-bison-topaz
EGFR
Strong
8.6e-10 M
True
25.8 kDa
241
id: radiant-otter-marble
EGFR
Strong
2.4e-9 M
True
25.8 kDa
241
id: mellow-ram-sand
EGFR
Strong
1.8e-9 M
True
25.8 kDa
241
id: rough-quail-granite
EGFR
Strong
2.1e-9 M
True
25.8 kDa
241
id: strong-mole-onyx
EGFR
Strong
2.4e-9 M
True
25.9 kDa
241
id: vast-boar-granite
EGFR
Strong
3.3e-9 M
True
25.9 kDa
241
id: frozen-fox-granite
PD-L1
Strong
8.1e-9 M
True
13.5 kDa
120
id: noble-panda-granite
PD-L1
Strong
1.5e-8 M
True
13.6 kDa
120
id: quick-hawk-opal
EGFR
Strong
2.4e-8 M
True
25.8 kDa
241
id: mellow-ram-reed
EGFR
Strong
2.7e-8 M
True
25.9 kDa
241
id: strong-tiger-flint
PD-L1
Strong
3.2e-8 M
True
13.5 kDa
120
id: vast-toad-flint
EGFR
Strong
4.9e-8 M
True
25.7 kDa
241
id: misty-ram-crystal
EGFR
Strong
4.9e-8 M
True
25.7 kDa
241
id: violet-vole-maple
PD-L1
Medium
9.3e-8 M
True
13.5 kDa
120
id: noble-vole-moss
PD-L1
Medium
1.6e-7 M
True
13.6 kDa
120
id: dark-crane-lava
PD-L1
Medium
1.7e-7 M
True
13.7 kDa
120
id: misty-raven-cedar
EGFR
Medium
2.1e-7 M
True
25.9 kDa
241
id: rapid-ox-reed
PD-L1
Medium
2.1e-7 M
True
13.4 kDa
120
id: brisk-shark-clay
PD-L1
Medium
3.2e-7 M
True
13.7 kDa
120
id: strong-hawk-bronze
PD-L1
Medium
5.5e-7 M
True
13.6 kDa
120
id: misty-zebra-cypress
PD-L1
Weak
7.8e-7 M
True
13.5 kDa
120