We designed a de novo binder targeting the stalk region of Nipah virus Glicoprotein G. We used 8gjg (de novo helical peptides trap) as fold-conditioned template to design de novo binder to stalk region of Nipah virus. We then redesign a non-interface regions of binder with ProteinMPNN.
id: silver-heron-dust

RBX1
Medium
5.7e-7 M
True
18.8 kDa
174
id: brisk-ant-cloud

RBX1
None
59.37
True
18.9 kDa
174
id: wild-ox-birch

RBX1
None
81.68
True
18.7 kDa
174
id: jade-bison-vine

RBX1
None
52.47
True
19.2 kDa
174
id: gentle-ibis-cloud

RBX1
None
82.44
True
18.9 kDa
174
id: misty-boar-marble

RBX1
None
59.09
True
19.1 kDa
174
id: bright-goat-ice

RBX1
None
75.69
True
18.9 kDa
174
id: young-otter-opal

Nipah Virus Glycoprotein G
None
77.24
True
19.3 kDa
172
id: quick-toad-ivy

Nipah Virus Glycoprotein G
None
85.28
True
18.7 kDa
162
id: frozen-panther-cloud

Nipah Virus Glycoprotein G
None
83.15
True
18.9 kDa
162
id: strong-vole-ember
No preview available
--
--
--
--
--
150
id: azure-zebra-cloud

RBX1
0.92
72.32
--
16.0 kDa
150
id: soft-heron-orchid

RBX1
0.88
59.28
--
16.1 kDa
150
id: scarlet-shark-ash

RBX1
0.90
71.87
--
16.7 kDa
150
id: swift-lynx-dust

RBX1
0.95
66.28
--
17.1 kDa
150
id: bright-ram-clay
No preview available
--
--
--
--
--
150
id: violet-crow-opal

RBX1
0.89
73.85
--
15.8 kDa
150
id: solid-mole-lotus

RBX1
0.91
81.87
--
16.8 kDa
150
id: amber-fox-vine
No preview available
--
--
--
--
--
130
id: jade-heron-wave

RBX1
0.74
65.42
--
17.0 kDa
150
id: steady-kiwi-topaz

RBX1
0.91
76.52
--
17.4 kDa
150