This workflow uses co-TIMED, a modified version of the TIMED model, to design sequences for a protein in the context of its binding partner. The generated sequences are then filtered based on predicted usability (NetSolP), structural predictions (ColabFold), and binding scores (BUDE FF).
id: silver-crow-birch

EGFR
None
--
True
5.2 kDa
47
id: amber-boar-snow

EGFR
None
--
True
5.2 kDa
47
id: swift-fox-ice

EGFR
None
--
True
5.3 kDa
47
id: young-hawk-ash

EGFR
None
--
True
5.5 kDa
47
id: noble-orca-onyx

EGFR
None
--
True
5.4 kDa
47
id: noble-falcon-fern

EGFR
None
--
True
5.3 kDa
47
id: dark-toad-maple

EGFR
None
--
True
5.4 kDa
47
id: gentle-panda-leaf

EGFR
None
--
True
5.4 kDa
47
id: rapid-ox-vine

EGFR
None
--
True
5.3 kDa
47
id: calm-cat-onyx

EGFR
None
--
True
5.4 kDa
47
id: bright-mole-frost

EGFR
None
--
True
5.4 kDa
47
id: frozen-goat-lotus

EGFR
Weak
8.2e-6 M
True
5.3 kDa
47
id: lunar-otter-lava

EGFR
None
--
True
5.3 kDa
47