Used BoltzGen to design de novo binders targeting epitopes on Nipah virus attachment glycoprotein (NiV-G). Generated diverse epitope patches on the target surface using interface analysis and SASA-based hotspot detection. Designed binders with lengths 70-140 amino acids against selected epitopes. Predicted binder-target complexes using Boltz2. Ranked candidates by pDockQ score from ipSAE analysis to identify the most promising binding geometries.