BindCraft was run on the full receptor structure to generate backbones. While no trajectories succeeded the MPNN sequence design stage, we extracted failed trajectories with ipTM with >=0.9. Sequence redesign to rescue the backbones was then performed using SolubleCaliby with 16 ensembles generated using ProtPardelle-1c. 20 sequences per backbone ensemble were generated, and filtered using ipSAE_min > 0.61 and SoluProt score > 0.5
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