AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

AlphaProteo binder backbones resequenced with ProteinMPNN at T=0.5 and SynthIDBio-sequence watermarking with non-distortionary keys.

Proteins (270)

TableGrid

GDGoogle DeepMind

id: silent-ox-pine

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.8e-6 M

True

9.1 kDa

id: rapid-crow-ivy

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.7e-6 M

True

10.7 kDa

id: green-dove-pearl

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.6e-6 M

True

8.8 kDa

id: ivory-panther-leaf

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.5e-6 M

True

13.3 kDa

120

id: vast-yak-lotus

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.4e-6 M

True

11.3 kDa

id: ivory-otter-cypress

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.4e-6 M

True

11.3 kDa

id: misty-heron-frost

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.3e-6 M

True

13.2 kDa

118

id: green-kiwi-ivy

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.3e-6 M

True

12.8 kDa

118

id: dark-quail-maple

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.3e-6 M

True

8.8 kDa

id: young-falcon-plume

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.3e-6 M

True

12.9 kDa

120

id: mellow-ram-bronze

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.3e-6 M

True

12.5 kDa

118

id: rapid-dove-moss

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.3e-6 M

True

12.4 kDa

118

id: rough-zebra-cloud

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.3e-6 M

True

14.6 kDa

136

id: silver-heron-leaf

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.2e-6 M

True

10.5 kDa

id: radiant-toad-bronze

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

1.2e-6 M

True

9.0 kDa

id: scarlet-bison-quartz

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Weak

1.1e-6 M

True

14.8 kDa

136

id: quiet-moth-ash

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Medium

9.7e-7 M

True

9.9 kDa

101

id: crimson-bison-crystal

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

PD-L1

Binding

Weak

9.2e-7 M

True

13.0 kDa

118

id: young-cobra-dust

Binder

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

Human VEGF110

Binding

Medium

8.1e-7 M

True

13.9 kDa

127

id: amber-kiwi-flint

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Medium

5.2e-7 M

True

7.4 kDa

id: swift-deer-dust

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Medium

5.0e-7 M

Expressed

True

Mol. Weight

7.3 kDa

AA Length