AlphaProteo backbone + ProteinMPNN (no watermark)

AlphaProteo binder backbones resequenced with ProteinMPNN at T=0.1, without watermark. Control arm of the SynthIDBio in vitro validation.

Proteins (225)

TableGrid

GDGoogle DeepMind

id: deep-ram-lotus

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.6e-6 M

True

9.2 kDa

id: radiant-gecko-lava

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.4e-6 M

True

10.6 kDa

id: frozen-lynx-pearl

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.4e-6 M

True

11.5 kDa

id: deep-moth-iron

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.4e-6 M

True

11.2 kDa

id: silent-bat-thorn

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.3e-6 M

True

12.2 kDa

105

id: quiet-mole-cloud

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.3e-6 M

True

10.6 kDa

id: gentle-gecko-vine

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.3e-6 M

True

12.7 kDa

120

id: quick-boar-leaf

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.3e-6 M

True

13.5 kDa

120

id: lunar-raven-ember

Binder

Peptide

AlphaProteo backbone + ProteinMPNN (no watermark)

No preview available

Target

SARS-CoV-2 RBD

Binding

Weak

1.2e-6 M

True

9.7 kDa

101

id: ivory-boar-snow

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.2e-6 M

True

11.7 kDa

105

id: rapid-gecko-thorn

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.2e-6 M

True

11.2 kDa

id: silent-bison-pine

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Weak

1.1e-6 M

True

14.9 kDa

136

id: vast-owl-opal

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Weak

1.1e-6 M

True

12.3 kDa

120

id: shy-vole-vine

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

Human VEGF110

Binding

Weak

1.1e-6 M

True

14.7 kDa

133

id: quick-kiwi-maple

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Weak

1.1e-6 M

True

9.7 kDa

100

id: amber-zebra-maple

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Weak

1.1e-6 M

True

15.0 kDa

136

id: noble-bee-birch

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Weak

1.1e-6 M

True

10.7 kDa

id: noble-mole-wave

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

Human VEGF110

Binding

Medium

1.0e-6 M

True

12.9 kDa

119

id: noble-toad-clay

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

Human VEGF110

Binding

Medium

9.6e-7 M

True

13.0 kDa

119

id: green-ram-granite

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Medium

5.7e-7 M

True

11.9 kDa

109

id: gentle-seal-lava

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

PD-L1

Binding

Medium

5.2e-7 M

Expressed

True

Mol. Weight

11.2 kDa

AA Length