We start from the structure of a known interaction of the antigen (in this case, 2vsm), and we set some of the residues in the interface as constant in space, and as part of a nanobody loop, and then we use boltzgen to design a scaffold and the rest of the loop.
id: silent-hawk-wave

Nipah Virus Glycoprotein G
None
78.40
False
13.7 kDa
134
id: steady-eagle-ice

Nipah Virus Glycoprotein G
None
83.90
True
13.9 kDa
126
id: scarlet-orca-marble

Nipah Virus Glycoprotein G
None
79.49
False
13.5 kDa
128
id: rough-eagle-birch

Nipah Virus Glycoprotein G
None
76.70
False
13.6 kDa
128
id: pale-bat-frost

Nipah Virus Glycoprotein G
None
83.02
True
13.7 kDa
126
id: noble-cobra-pearl

Nipah Virus Glycoprotein G
None
81.99
True
13.7 kDa
128
id: solid-crane-opal

Nipah Virus Glycoprotein G
None
80.28
True
13.5 kDa
125
id: rapid-toad-maple

Nipah Virus Glycoprotein G
0.77
83.75
--
13.9 kDa
126