Latent-X + Boltz2 | Proteinbase

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Latent-X + Boltz2 | Proteinbase

BABastien Armstrong

Latent-X + Boltz2

The binders were designed with Latent-X then validated with Boltz2 and their ipSAE scores.

Description

The binders were designed with Latent-X then validated with Boltz2 and their ipSAE scores.

About

1proteins generated

1 / 1proteins validated

100%expression rate

Targets

Nipah Virus Glycoprotein G

1 binder•6.9e-8 avg KD

Human Serum Albumin

0 binders•-- avg KD

Design Class

other 89%

miniprotein 11%

Binding Strength

unknown 84%

medium 5%

none 5%

strong 5%

Expressed

unknown 95%

true 5%

De Novo

unknown 95%

yes 5%

Classification

mainly Alpha 74%

alpha Beta 26%

Architecture

up Down Bundle 32%

alpha Horseshoe 21%

3 Layer Aba Sandwich 16%

2 Layer Sandwich 11%

orthogonal Bundle 11%

alpha Beta Complex 5%

sandwich 5%

Collections

Nipah Binder Competition: Main Submissions

Adaptyv Bio

MOG-DFM Spotlight

Programmable Biology Group

ProtRL Validation

CRG Ferruz Lab

Adaptyv EGFR Competition Round 1

Adaptyv Bio

EvoDiff Validation

Microsoft Research

Pro-1 validation

Michael Hla

RFdiffusion re-validation

Adaptyv Bio

Adaptyv EGFR Competition Round 2

Adaptyv Bio

DSM Synteract Round 1

Gleghorn Lab X Synthyra

EGFR Round 1 Second Submission

Gitter Lab

Evolved 2024 Bio x ML Team Silica EGFR Nanobodies

BioLM

BindCraft1 publication re-validation

EPFL-LPDI

Mosaic Multispecifics

Escalante Bio

Mosaic Development

Escalante Bio

Nipah Competition Results

Adaptyv Bio

BoltzGen Release

Massachusetts Institute of Technology

Cradle EGFR Competition Follow Up

Cradle

Proteins (1)

TableGrid

BABastien Armstrong

id: vast-zebra-lotus

Binder

Other

Latent-X + Boltz2

vast-zebra-lotus

Multiple (2)

Medium (4), Strong (2)

True

12.5 kDa

120

Rows per page

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