2vsm+FastRelax+LigandMPNN+AF3 | Proteinbase

Proteins
Collections
Design Methods
Targets
Competitions

2vsm+FastRelax+LigandMPNN+AF3

FastRelax in PyRosetta to optimise the protein-protein complex. Optimise ligand chain (EPHRIN-B2) using LigandMPNN. Sequences with high overall confidence are validated with AlphaFold3.

Description

FastRelax in PyRosetta to optimise the protein-protein complex. Optimise ligand chain (EPHRIN-B2) using LigandMPNN. Sequences with high overall confidence are validated with AlphaFold3.

2vsm+FastRelax+LigandMPNN+AF3 | Proteinbase

Proteins (7)

TableGrid

id: scarlet-zebra-leaf

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

scarlet-zebra-leaf

Nipah Virus Glycoprotein G

0.00

87.54

--

15.3 kDa

138

id: shy-crane-snow

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

shy-crane-snow

Nipah Virus Glycoprotein G

0.00

86.08

--

15.3 kDa

138

id: frozen-goat-clay

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

frozen-goat-clay

Nipah Virus Glycoprotein G

0.08

86.43

--

15.3 kDa

138

id: amber-goat-snow

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

amber-goat-snow

Nipah Virus Glycoprotein G

0.05

87.82

--

15.4 kDa

138

id: violet-seal-cedar

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

violet-seal-cedar

Nipah Virus Glycoprotein G

0.00

87.92

--

15.4 kDa

138

id: bright-crane-topaz

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

bright-crane-topaz

Nipah Virus Glycoprotein G

0.00

86.91

--

15.3 kDa

138

id: solid-panther-crystal

Binder

Other

2vsm+FastRelax+LigandMPNN+AF3

solid-panther-crystal

Nipah Virus Glycoprotein G

0.01

86.60

--

15.3 kDa

138

Rows per page

1-7 of 7

About

7proteins generated

0 / 7proteins validated

Targets

Nipah Virus Glycoprotein G

0 binders•-- avg KD

Design Class

other 100%

Binding Strength

unknown 100%

Expressed

unknown 100%

Classification

alpha Beta 100%

Architecture

unknown 100%

Collections

MOG-DFM Spotlight

Programmable Biology Group

ProtRL Validation

CRG Ferruz Lab

Adaptyv EGFR Competition Round 1

Adaptyv Bio

EvoDiff Validation

Microsoft Research

Pro-1 validation

Michael Hla

RFdiffusion re-validation

Adaptyv Bio

Adaptyv EGFR Competition Round 2

Adaptyv Bio

DSM Synteract Round 1

Gleghorn Lab X Synthyra

EGFR Round 1 Second Submission

Gitter Lab

Evolved 2024 Bio x ML Team Silica EGFR Nanobodies

BioLM

BindCraft1 publication re-validation

EPFL-LPDI

Mosaic Multispecifics

Escalante Bio

Mosaic Development

Escalante Bio

Nipah Binder Competition: Main Submissions

Adaptyv Bio

BoltzGen Release

Massachusetts Institute of Technology

Cradle EGFR Competition Follow Up

Cradle