used amino acid contacts that were also highly accessible as hotspots in RFDiffusion to generate various length binders. Then input best results into Alphafold multimer in complex with protein to validate interaction in the desired region.
Description
used amino acid contacts that were also highly accessible as hotspots in RFDiffusion to generate various length binders. Then input best results into Alphafold multimer in complex with protein to validate interaction in the desired region.
