Rational Antibody-Based Binder Design (RABBD) | Proteinbase

Proteins
Collections
Design Methods
Targets
Competitions

Rational Antibody-Based Binder Design (RABBD) | Proteinbase

JOJoseph Odongo

Rational Antibody-Based Binder Design (RABBD)

This method generates high-affinity antibody-like binders through rational engineering of complementarity-determining regions (CDRs) based on structural analysis of the target protein.

Description

This method generates high-affinity antibody-like binders through rational engineering of complementarity-determining regions (CDRs) based on structural analysis of the target protein.

About

3proteins generated

0 / 3proteins validated

Targets

Nipah Virus Glycoprotein G

0 binders•-- avg KD

Design Class

nanobody 100%

Binding Strength

unknown 100%

Expressed

unknown 100%

Classification

mainly Beta 100%

Architecture

sandwich 100%

Collections

MOG-DFM Spotlight

Programmable Biology Group

ProtRL Validation

CRG Ferruz Lab

Adaptyv EGFR Competition Round 1

Adaptyv Bio

EvoDiff Validation

Microsoft Research

Pro-1 validation

Michael Hla

RFdiffusion re-validation

Adaptyv Bio

Adaptyv EGFR Competition Round 2

Adaptyv Bio

DSM Synteract Round 1

Gleghorn Lab X Synthyra

EGFR Round 1 Second Submission

Gitter Lab

Evolved 2024 Bio x ML Team Silica EGFR Nanobodies

BioLM

BindCraft1 publication re-validation

EPFL-LPDI

Mosaic Multispecifics

Escalante Bio

Mosaic Development

Escalante Bio

Nipah Binder Competition: Main Submissions

Adaptyv Bio

BoltzGen Release

Massachusetts Institute of Technology

Cradle EGFR Competition Follow Up

Cradle

Proteins (3)

TableGrid

JOJoseph Odongo

id: crimson-ant-rose

Binder

Nanobody

Rational Antibody-Based Binder Design (RABBD)

crimson-ant-rose

Nipah Virus Glycoprotein G

0.48

71.67

--

13.1 kDa

114

JOJoseph Odongo

id: ivory-ox-lava

Binder

Nanobody

Rational Antibody-Based Binder Design (RABBD)

ivory-ox-lava

Nipah Virus Glycoprotein G

0.39

77.22

--

12.2 kDa

110

JOJoseph Odongo

id: noble-bear-flint

Binder

Nanobody

Rational Antibody-Based Binder Design (RABBD)

noble-bear-flint

Nipah Virus Glycoprotein G

0.68

74.28

--

12.9 kDa

111

Rows per page

1-3 of 3