JointDiff-x-conditional | Proteinbase

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JointDiff-x-conditional | Proteinbase

JointDiff-x-conditional

Conditioned on the viral epitope in 2VSM Selected motifs from the human receptor Motif scaffolding with generative model JointDiff-x-conditional that simultaneously generates protein sequence and structure…

Description

Conditioned on the viral epitope in 2VSM Selected motifs from the human receptor Motif scaffolding with generative model JointDiff-x-conditional that simultaneously generates protein sequence and structure. Filtered based on the portion of epitope that is within close proximity of the generated structures

Proteins (10)

TableGrid

id: dark-lynx-plume

Binder

Other

JointDiff-x-conditional

dark-lynx-plume

Nipah Virus Glycoprotein G

0.60

34.63

--

14.7 kDa

137

id: quick-swan-ice

Binder

Other

JointDiff-x-conditional

quick-swan-ice

Nipah Virus Glycoprotein G

0.46

32.15

--

15.1 kDa

137

id: lunar-boar-maple

Binder

Other

JointDiff-x-conditional

lunar-boar-maple

Nipah Virus Glycoprotein G

0.00

25.61

--

14.5 kDa

137

id: green-ibis-willow

Binder

Other

JointDiff-x-conditional

green-ibis-willow

Nipah Virus Glycoprotein G

0.00

31.60

--

14.7 kDa

137

id: crimson-bear-thorn

Binder

Other

JointDiff-x-conditional

crimson-bear-thorn

Nipah Virus Glycoprotein G

0.40

26.60

--

14.7 kDa

137

id: hollow-yak-willow

Binder

Other

JointDiff-x-conditional

hollow-yak-willow

Nipah Virus Glycoprotein G

0.38

37.06

--

14.9 kDa

137

id: frozen-panda-marble

Binder

Other

JointDiff-x-conditional

frozen-panda-marble

Nipah Virus Glycoprotein G

0.39

31.69

--

15.2 kDa

137

id: lunar-owl-pine

Binder

Other

JointDiff-x-conditional

lunar-owl-pine

Nipah Virus Glycoprotein G

0.56

29.04

--

15.2 kDa

137

id: pale-lynx-willow

Binder

Other

JointDiff-x-conditional

pale-lynx-willow

Nipah Virus Glycoprotein G

0.12

26.42

--

14.4 kDa

137

id: jade-gecko-stone

Binder

Other

JointDiff-x-conditional

jade-gecko-stone

Nipah Virus Glycoprotein G

0.50

32.87

--

14.3 kDa

137

Rows per page

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About

10proteins generated

0 / 10proteins validated

Targets

Nipah Virus Glycoprotein G

0 binders•-- avg KD

Design Class

other 100%

Binding Strength

unknown 100%

Expressed

unknown 100%

Classification

alpha Beta 40%

few Secondary Structures 30%

mainly Beta 20%

mainly Alpha 10%

Architecture

unknown 100%

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DSM Synteract Round 1

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EGFR Round 1 Second Submission

Gitter Lab

Evolved 2024 Bio x ML Team Silica EGFR Nanobodies

BioLM

BindCraft1 publication re-validation

EPFL-LPDI

Mosaic Multispecifics

Escalante Bio

Mosaic Development

Escalante Bio

Nipah Binder Competition: Main Submissions

Adaptyv Bio

BoltzGen Release

Massachusetts Institute of Technology

Cradle EGFR Competition Follow Up

Cradle