FlexMPNN+ | Proteinbase

Proteins
Collections
Design Methods
Targets
Competitions

FlexMPNN+ | Proteinbase

FlexMPNN+

Monte Carlo geometric simulation enhanced ProteinMPNN accounting for unfolding nuclei

Description

Monte Carlo geometric simulation enhanced ProteinMPNN accounting for unfolding nuclei

About

25proteins generated

2 / 25proteins validated

100%expression rate

Targets

Nipah Virus Glycoprotein G

1 binder•2.7e-8 avg KD

Human Serum Albumin

0 binders•-- avg KD

Design Class

other 100%

Binding Strength

unknown 88%

none 8%

strong 4%

Expressed

unknown 92%

true 8%

De Novo

unknown 92%

no 8%

Classification

alpha Beta 100%

Architecture

sandwich 56%

unknown 44%

Collections

Nipah Binder Competition: Main Submissions

Adaptyv Bio

MOG-DFM Spotlight

Programmable Biology Group

ProtRL Validation

CRG Ferruz Lab

Adaptyv EGFR Competition Round 1

Adaptyv Bio

EvoDiff Validation

Microsoft Research

Pro-1 validation

Michael Hla

RFdiffusion re-validation

Adaptyv Bio

Adaptyv EGFR Competition Round 2

Adaptyv Bio

DSM Synteract Round 1

Gleghorn Lab X Synthyra

EGFR Round 1 Second Submission

Gitter Lab

Evolved 2024 Bio x ML Team Silica EGFR Nanobodies

BioLM

BindCraft1 publication re-validation

EPFL-LPDI

Mosaic Multispecifics

Escalante Bio

Mosaic Development

Escalante Bio

Nipah Competition Results

Adaptyv Bio

BoltzGen Release

Massachusetts Institute of Technology

Cradle EGFR Competition Follow Up

Cradle

Proteins (2)

TableGrid

id: deep-crow-ivy

Binder

Other

FlexMPNN+

deep-crow-ivy

Multiple (2)

Strong (6)

True

15.8 kDa

137

id: bright-swan-oak

Binder

Other

FlexMPNN+

bright-swan-oak

Nipah Virus Glycoprotein G

None

83.21

True

15.8 kDa

137

Rows per page

1-2 of 2