BoltzGen + Protein Hunter (sequence refinement)

BoltzGen was used to generate new nanobody binders to the target protein, and the Protein Hunter (Chai version) pipeline for sequence refinement was used to iteratively improve the best models from BoltzGen.

Description

Proteins (4)

TableGrid

Rrdgcnc

id: quiet-heron-crystal

Binder

Nanobody

BoltzGen + Protein Hunter (sequence refinement)

Target

Nipah Virus Glycoprotein G

0.64

80.82

14.0 kDa

127

id: dark-otter-ice

Binder

Nanobody

BoltzGen + Protein Hunter (sequence refinement)

Target

Nipah Virus Glycoprotein G

0.35

84.27

13.2 kDa

123

id: deep-lynx-cypress

Binder

Other

BoltzGen + Protein Hunter (sequence refinement)

Target

Nipah Virus Glycoprotein G

0.78

82.80

12.8 kDa

118

id: young-zebra-sand

Binder

Other

BoltzGen + Protein Hunter (sequence refinement)

Target

Nipah Virus Glycoprotein G

0.79

84.19

12.9 kDa

118