Affibody using BAGEL | Proteinbase

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Affibody using BAGEL

We take the classic affibody scaffold and optimise the 13 aminoacid variable part using in silico directed evolution via BAGEL (https://github.com/softnanolab/bagel)

Description

We take the classic affibody scaffold and optimise the 13 aminoacid variable part using in silico directed evolution via BAGEL (https://github.com/softnanolab/bagel)

Affibody using BAGEL | Proteinbase

Proteins (3)

TableGrid

id: calm-bear-orchid

Binder

Affibody

Affibody using BAGEL

calm-bear-orchid

Nipah Virus Glycoprotein G

0.00

88.04

--

6.6 kDa

58

id: noble-zebra-crystal

Binder

Miniprotein

Affibody using BAGEL

noble-zebra-crystal

Nipah Virus Glycoprotein G

0.80

79.71

--

6.8 kDa

58

id: quiet-crane-wave

Binder

Affibody

Affibody using BAGEL

quiet-crane-wave

Nipah Virus Glycoprotein G

0.00

88.22

--

6.6 kDa

58

Rows per page

1-3 of 3

About

3proteins generated

0 / 3proteins validated

Targets

Nipah Virus Glycoprotein G

0 binders•-- avg KD

Design Class

affibody 67%

miniprotein 33%

Binding Strength

unknown 100%

Expressed

unknown 100%

Classification

mainly Alpha 100%

Architecture

unknown 100%

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Programmable Biology Group

ProtRL Validation

CRG Ferruz Lab

Adaptyv EGFR Competition Round 1

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EvoDiff Validation

Microsoft Research

Pro-1 validation

Michael Hla

RFdiffusion re-validation

Adaptyv Bio

Adaptyv EGFR Competition Round 2

Adaptyv Bio

DSM Synteract Round 1

Gleghorn Lab X Synthyra

EGFR Round 1 Second Submission

Gitter Lab

Evolved 2024 Bio x ML Team Silica EGFR Nanobodies

BioLM

BindCraft1 publication re-validation

EPFL-LPDI

Mosaic Multispecifics

Escalante Bio

Mosaic Development

Escalante Bio

Nipah Binder Competition: Main Submissions

Adaptyv Bio

BoltzGen Release

Massachusetts Institute of Technology

Cradle EGFR Competition Follow Up

Cradle