scFv shy-ibis-stone

kang / shy-ibis-stone

Type

scFv

Binding

Nipah Virus Glycoprotein G

Strong

Expressed

Yes

Ref

m2_41-6_4_keep_int_res

Collections

KSubmission 4

ANipah Binder Competition: Main Submissions

ANipah Binder Competition Results

Awards

#29Nipah Binder Competition

Sequence (250 AA)

VQLVQSGGGLVQPGGSLRLSCAASGFDISKYYMSWVRQAPGKGLEWVSSISGSGDVTYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDREDIVVVPAPRGYYYYYYMDVWGQGTTVTVSSGGGGSGGGGSQSVVTQPPSVSAAPGQKVTISCSGSSSNIGTNHLSWYQQVPGTAPKLLIYDNDKRPSGIPDRFSGSKSGTSASLAISGLQSEDEADYYCATWDDSLHAWVFGGGTKLTVL

Computational Metrics

Experimental Metrics

Design Class

scFv

Isoelectric Point

6.13pH

Molecular Weight

2.65e+4Da

Download CIF

Loading structure viewer...

Binding

Yes

Binding Strength

Strong

1.3e-8M

Kon

2.2e+4M

Koff

2.8e-4M

Neutralization

None

Download raw data

Loading kinetic curves...

Design Method

This protein was designed using KSHM Antibody Language Model + LigandMPNN