scFv frozen-yak-granite

kang / frozen-yak-granite

Type

scFv

Binding

Nipah Virus Glycoprotein G

Strong

Human Serum Albumin

None

Expressed

Yes

Ref

d2_41-6_2_keep_int_res

Collections

KSubmission 4

ANipah Binder Competition: Main Submissions

ANipah Competition Results

Awards

#40Nipah Binder Competition

Sequence (250 AA)

VQLVQSGGGLVQPGGSLRLSCAASGFDISKYYMSWVRQAPGKGLEWVSSISGDGVVSYYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARDREDIVVVPAPRGYYYYYYMDVWGQGTTVTVSSGGGGSGGGGSQSVVTQPPSVSAAPGQKVTISCSGSSSNIGTNHLSWYQQVPGTAPKLLIYDNDKRPSGIPDRFSGSKSGTSASLAISGLQSEDEADYYCATWDDSLHAWVFGGGTKLTVL

Computational Metrics

Experimental Metrics

Design Class

scFv

Isoelectric Point

6.13pH

Molecular Weight

2.65e+4Da

Download CIF

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Binding

Yes

Binding Strength

Strong

2.5e-8M

Kon

1.8e+4M-1s-1

Koff

4.6e-4s-1

Download raw data

Kinetic Curves (SPR)

Fit Model

Concentration

1.00 nM

3.20 nM

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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Design Method

This protein was designed using KSHM Antibody Language Model + LigandMPNN