Backbone 11 against VEGF-A: the AlphaProteo parent sequence pale-dove-moss and its 20 ProteinMPNN redesigns without a watermark, with distortionary SynthIDBio keys and with non-distortionary SynthIDBio keys. Part of SynthIDBio: watermarked protein binders. Source data: GitHub repository (CC BY 4.0).
id: pale-dove-moss

Human VEGF110
Strong
5.4e-10 M
True
14.2 kDa
133
id: jade-fox-ruby

Human VEGF110
Strong
1.9e-8 M
True
14.7 kDa
133
id: brisk-dove-ruby

Human VEGF110
Strong
3.3e-8 M
True
14.7 kDa
133
id: young-hawk-iron

Human VEGF110
Medium
1.3e-7 M
True
14.3 kDa
133
id: pale-otter-cloud

Human VEGF110
Medium
1.7e-7 M
True
14.7 kDa
133
id: green-toad-cedar

Human VEGF110
Medium
1.9e-7 M
True
14.5 kDa
133
id: steady-orca-frost

Human VEGF110
Medium
3.0e-7 M
True
14.6 kDa
133
id: shy-vole-vine

Human VEGF110
Weak
1.1e-6 M
True
14.7 kDa
133
id: swift-orca-frost

Human VEGF110
None
79.46
True
8.7 kDa
78
id: swift-quail-vine

Human VEGF110
None
88.22
True
8.8 kDa
78
id: jade-boar-birch

Human VEGF110
None
87.79
False
14.6 kDa
133
id: noble-seal-lotus

Human VEGF110
None
86.27
True
14.4 kDa
133
id: misty-ram-lava

Human VEGF110
None
89.40
True
14.5 kDa
133
id: radiant-lion-ruby

Human VEGF110
None
87.49
True
14.6 kDa
133
id: strong-moth-sand

Human VEGF110
None
84.28
True
14.7 kDa
133
id: quiet-cobra-reed

Human VEGF110
None
87.36
True
14.5 kDa
133
id: amber-moth-willow

Human VEGF110
None
85.18
True
14.4 kDa
133
id: dark-panda-thorn

Human VEGF110
None
88.74
True
14.4 kDa
133
id: violet-cat-crystal

Human VEGF110
None
86.35
True
9.0 kDa
78
id: dark-raven-lava

Human VEGF110
None
88.09
True
14.5 kDa
133
id: frozen-raven-quartz

Human VEGF110
None
88.13
True
14.5 kDa
133