Protein rough-eagle-ash

Type

Other

Binding

Nipah Virus Glycoprotein G

Strong

Expressed

Yes

Ref

antiHNV_C4

Collections

Awards

Sequence (149 AA)

MSPYKKAIEITKRLLELLLSNPELAKKNLGGIATLISLLALISALDGTLDEKDIEPYIKKLEESLGSGGSGLDEYAELLAEGWKRKVDAGQDIKFTIKFQEFSPNLWGLEPEEIYEAAMKAANSIEGAEVTVEENGDYKTITIKKAPGG

Design Class

Other

Isoelectric Point

4.71pH

Molecular Weight

1.63e+4Da

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Binding

Yes

Binding Strength

Strong

3.3e-9M

Kon

3.6e+4M

Koff

1.2e-4M

Neutralization

Full

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This protein was designed using BLRFdiffusion

Rosetta + RFDiffusion for backbone gen MPNN for sequence design Templated AF2 for in silico selection Iterative wet lab-dry lab testing.