scFv rough-bison-maple

Andrew Huang / rough-bison-maple

Type

scFv

Binding

Nipah Virus Glycoprotein G

Strong

Expressed

Yes

Ref

QVQLQESGPGVVKPSETLSLTCAVSGGSISDTYRWSWIRQPPGKGLEWIGYIYGSATSTYYNPSLKSRVTISKDMSKNQFSLNLNSVTAADTAVYYCARDYQYYYSGSYPTPHNWFDVWGPGVLVTVSGGSGGSGGSGGSGGDIQMTQSPSSLSASVGDRVTITCRASQGIIDYLSWYQQKPGKAPKLLISTASNLESGVPSRFSGSGSGTEFTLTISSLQPEDFATYSCQQGYTTPYTFGQGTKVEIK

Collections

AMultimodel-validated ScFv Mutants

ANipah Binder Competition: Main Submissions

ANipah Binder Competition Results

Awards

#3Nipah Binder Competition

Sequence (249 AA)

Computational Metrics

Experimental Metrics

Design Class

scFv

Isoelectric Point

7.76pH

Molecular Weight

2.66e+4Da

Download CIF

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Binding

Yes

Binding Strength

Strong

7.2e-10M

Kon

1.5e+5M

Koff

1.0e-4M

Neutralization

None

Download raw data

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Design Method

This protein was designed using AHESMfold, RFdiffusion, and rational design