Miniprotein frozen-raven-maple

Max Beining / frozen-raven-maple

Type

Miniprotein

Binding

Nipah Virus Glycoprotein G

Medium

Human Serum Albumin

None

Expressed

Yes

Ref

N1017

Collections

MSubmission 6

ANipah Binder Competition: Main Submissions

ANipah Competition Results

Awards

#76Nipah Binder Competition

Sequence (82 AA)

EAELIAEYEKRDAEELAALEADVKELLALLKKLGAEKYKDLEDFLKSELAAAKEDPRLRIYLKGVIKKEKARLTAELAAKEA

Computational Metrics

Experimental Metrics

Design Class

Miniprotein

Isoelectric Point

5.13pH

Molecular Weight

9229.58Da

Download CIF

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Binding

Yes

Binding Strength

Medium

7.6e-8M

Kon

5.5e+3M-1s-1

Koff

4.1e-4s-1

Download raw data

Kinetic Curves (SPR)

Fit Model

Concentration

1.00 nM

3.20 nM

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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Design Method

This protein was designed using MBRFdiffusion (full,partial) + PMPNN + AlphaFold/Boltz pred + Rosetta filtering