Nanobody
NiV_RBinder_001|Antibody-like
Sequence (114 AA)
QVQLIRSGREVLKVGSSMKVSCKASSSFKANLWWVWVRQAPGQGLEWMGGYTFKRWKWKRRFTISADTSKNTAYLYMNSLRAEDTAVYYCAKTATQHEYHCCTWGQGTLVTVSS
No experimental data
This protein hasn't been validated in the lab yet.
This protein was designed using JORational Antibody-Based Binder Design (RABBD)
Human VH domain; CDR1 Design: Aromatic-rich (Y, W, F) for RBD cavity recognition; CDR2 Design: Charged residues (K, R) for electrostatic interactions; CDR3 Design: Mixed hydrophobic/aromatic for high affinity; Optimization: 10 conservative mutations for novelty; ipSAE Target: >40