Karen Paco

Computational and experimental biologist focused on protein and antibody foundation models. Builds deep learning and structure-aware generative models and integrates multi-omics with structural/biophysical assays to design better therapeutic proteins and antibodies.

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35proteins designed

3proteins validated

0binders

Collections created (1)

Submission 7

Karen Paco • 2 months ago

Design methods created (2)

RFDifussion

31 proteins generated

2 proteins tested

RFdiffusion–MPNN–Boltz–ipSAE

1 proteins generated

1 proteins tested

Design Methods Used

RFDifussion 67%

RFdiffusion–MPNN–Boltz–ipSAE 33%

Protein Type

scFv 100%

Binding Targets

Nipah Virus Glycoprotein G 75%

Human Serum Albumin 25%

Proteins Designed (35)

TableGrid

KPKaren Paco

id: crimson-ram-dust

Binder

scFv

RFdiffusion–MPNN–Boltz–ipSAE

Multiple (2)

0.47

68.82

True

26.1 kDa

250

id: hollow-shark-ash

Binder

scFv

RFDifussion

Target

Nipah Virus Glycoprotein G

None

69.51

True

26.4 kDa

250

id: deep-raven-topaz

Binder

scFv

RFDifussion

Target

Nipah Virus Glycoprotein G

None

69.37

True

26.3 kDa

249

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

Proteins Designed (35)

TableGrid

KPKaren Paco

id: crimson-ram-dust

Binder

scFv

RFdiffusion–MPNN–Boltz–ipSAE

Multiple (2)

0.47

68.82

True

26.1 kDa

250

id: hollow-shark-ash

Binder

scFv

RFDifussion

Target

Nipah Virus Glycoprotein G

None

69.51

True

26.4 kDa

250

id: deep-raven-topaz

Binder

scFv

RFDifussion

Target

Nipah Virus Glycoprotein G

None

69.37

True

26.3 kDa

249

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible

KPKaren Paco

Private

Private Protein

This protein is not publicly visible