Miniprotein violet-cobra-crystal

Type

Miniprotein

Binding

PD-L1

Weak

Expressed

Yes

Ref

PDW_1386

Collections

Sequence (98 AA)

TEEEKKILELMKNGDLEKALELLEKSKDLSKFEKRHLGLLLLMAALQRKDRELARRVVELMAEKKVLTEETAATILALLEKLAPELVPEAEKILKEAL

Design Class

Miniprotein

Isoelectric Point

5.58pH

Molecular Weight

11.2kDa

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Binding

Yes

Binding Strength

Weak

K_D

1.3×10⁻⁶M

k_on

4.5×10⁴M^-1s^-1

k_off

5.8×10⁻²s^-1

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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This protein was designed using GDAlphaProteo (parent sequence)

Parameters

backboneAlphaProteo

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