Miniprotein vast-orca-lava

Type

Miniprotein

Binding

PD-L1

Strong

Expressed

Yes

Ref

PDW_1409

Collections

Sequence (118 AA)

TEEEIEKIKKEILKILEEIKKLLEKLPREKAREVAKKIKDYLLEKADAATDRKVRAAYIIALVILGAVLGGVLNGNPEAGLEAAREILDVVAEHAPELLPLILKALKEALELLKEMVA

Design Class

Miniprotein

Isoelectric Point

5.61pH

Molecular Weight

13.1kDa

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Binding

Yes

Binding Strength

Strong

K_D

2.7×10⁻⁸M

k_on

1.3×10⁴M^-1s^-1

k_off

3.2×10⁻⁴s^-1

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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This protein was designed using GDAlphaProteo (parent sequence)

Parameters

backboneAlphaProteo

watermarknone