Protein solid-otter-birch

gregory.coolen / solid-otter-birch

Type

Other

Binding

Nipah Virus Glycoprotein G

None

Expressed

Yes

Ref

mutant_('DB42W','TB67I','VB72I')

Collections

GSubmission 1

ANipah Binder Competition: Main Submissions

ANipah Competition Results

Sequence (150 AA)

VRIIVAPDTLTPSQVAELAYEELKALGFKRVLIVSVGDGRIWSGANLTAATLKALLKKEGIEVELIIVSVHITDEQRRRILDEIVERARELKVDGVLIVTDVPDEFAEAGAALVRDLVRRFAEELGIPVIVVLTHTGKAGEAIRAAVEAV

Computational Metrics

Experimental Metrics

Design Class

Other

Isoelectric Point

5.15pH

Molecular Weight

1.63e+4Da

Download CIF

Loading structure viewer...

Binding

Binding Strength

None

Download raw data

Kinetic Curves (SPR)

Concentration

1.00 nM

3.20 nM

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

Loading kinetic curves...

Design Method

This protein was designed using GBoltzGen + Physics based mutagenesis (double/triple-mutants)

These differ from the other sequences submitted with a similar method as they are double and triple mutants selected from single mutants with desirable effects, located at distant positions.