Miniprotein solid-falcon-dust

Type

Miniprotein

Binding

PD-L1

Strong

Expressed

Yes

Ref

PDW_1421

Collections

Sequence (97 AA)

SAEEKLAENALAMVKKLLEDALKSTDPQEVRSLLKAARDVTVTVLKRLSEELAKKLAEEVLKLIDEAEEKLPELPEEVAAVAREELGEIRKAIEELL

Design Class

Miniprotein

Isoelectric Point

4.70pH

Molecular Weight

10.8kDa

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Binding

Yes

Binding Strength

Strong

K_D

3.3×10⁻⁸M

k_on

4.9×10⁵M^-1s^-1

k_off

1.6×10⁻²s^-1

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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This protein was designed using GDAlphaProteo (parent sequence)

Parameters

backboneAlphaProteo

watermarknone