BoltzGen to target the disordered region of RBX1 (residues 1-32)
entities:
Specify a designed protein chain
- protein:
id: G
random number between 40 and 80 of designed residues (inclusive)
sequence: 40..80
Specification of the target which is extracted from a .cif file
- file:
path: 2LGV_model1.pdb
Which chain and residues in the .cif file to use as target (uses only chain A here)
include:
- chain:
id: A
Which regions of the target the design should or should NOT bind to
Here we specify that the design should bind to residues 1..32 on chain A and not bind to residues 33..100 on chain A
binding_types:
- chain:
id: A
binding: 1..32
not_binding: 33..100
Which regions of the target should have their structure specified
Here we keep structure specified (visible) region 39..97 of chain A
structure_groups:
- group:
visibility: 1
id: A
res_index: 39..97