alexis.dougha

Computational peptide design to inhibit protein-protein interactions

70proteins designed

0proteins validated

0binders

Collections created (1)

Submission 7

alexis.dougha • 19 days ago

Design methods created (2)

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

69 proteins generated

0 proteins tested

Boltzgen + AF3 webserver filtering

1 proteins generated

0 proteins tested

Design Methods Used

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization 100%

Protein Type

Other 10%

Peptide 90%

Binding Targets

Nipah Virus Glycoprotein G 100%

Proteins Designed (70)

TableGrid

Aalexis.dougha

id: rough-owl-orchid

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.76

62.54

1.4 kDa

id: brisk-panther-quartz

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.75

63.15

1.3 kDa

id: steady-falcon-cedar

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.72

62.46

1.3 kDa

id: frozen-boar-bronze

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.79

62.25

1.3 kDa

id: lunar-gecko-onyx

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.74

60.74

1.4 kDa

id: silent-ibis-cloud

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.79

66.99

1.3 kDa

id: scarlet-dove-ivy

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.76

63.78

1.3 kDa

id: violet-owl-quartz

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.74

61.27

1.3 kDa

id: quick-zebra-birch

Binder

Peptide

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.73

61.57

1.4 kDa

id: amber-toad-ice

Binder

Other

custom MSA (NCBI Virus) + Evodiff + AF3 filtering + AF3 iterative optimization

Target

Nipah Virus Glycoprotein G

0.76

61.48

1.2 kDa

Aalexis.dougha

Private

Private Protein