Miniprotein radiant-orca-iron | Proteinbase

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Miniprotein radiant-orca-iron | Proteinbase

PB

Programmable Biology Group / radiant-orca-iron

Type

Miniprotein

Binding

Human Calmodulin 1/CALM1 (holo, +CaCl2)

Medium

Human Calmodulin 1/CALM1 (apo, +EGTA)

None

Expressed

Yes

Ref

rfdiff_vanilla__design_944

Collections

PAllo-Designer CaM binders

Sequence (23 AA)

ATAAMIKTFQDVVVAAVREAREK

Sequence (23 AA)

ATAAMIKTFQDVVVAAVREAREK

Computational Metrics

Experimental Metrics

Design Class

Miniprotein

Isoelectric Point

8.63pH

Molecular Weight

2504.90Da

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Binding

Yes

Binding Strength

Medium, Strong

KD

4.7e-8M

Kon

1.3e+5M-1s-1

Koff

5.6e-3s-1

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Proteins
radiant-orca-iron

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Kinetic Curves (BLI)

Concentration

0.0 nM

100 nM

1000 nM