Miniprotein quiet-ram-thorn

Type

Miniprotein

Binding

SARS-CoV-2 RBD

Strong

Expressed

Yes

Ref

PDW_1157

Collections

Sequence (109 AA)

TEFTQQLQNAQDLLQQAQASTDAKESFGLINTALSGINELGSLSDAGKQLSLDAHTEFTAFKKSLGIIFSDGMTEEQIKATFQQMVEKTTLQQAQTLAQKLLSLVQRAS

Design Class

Miniprotein

Isoelectric Point

4.78pH

Molecular Weight

11.9kDa

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Binding

Yes

Binding Strength

Strong

K_D

3.7×10⁻⁸M

k_on

2.2×10⁵M^-1s^-1

k_off

7.7×10⁻³s^-1

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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This protein was designed using GDAlphaProteo (parent sequence)

Parameters

backboneAlphaProteo

watermarknone