Peptide misty-tiger-iron

Google DeepMind / misty-tiger-iron

Type

Peptide

Binding

SARS-CoV-2 RBD

Medium

Expressed

Yes

Ref

PDW_1177

Collections

DSynthIDBio: watermarked protein binders (Google DeepMind)

Sequence (101 AA)

RCRGELAVDKTAATPGDTVRASAKGTGTATVAGDRVFVVMLAFNQQGNEVSSASGRAACGDVAEAELTVPAGASKIKVFAGSGHPGLNTGFITDYAEIEVS

Computational Metrics

Experimental Metrics

Design Class

Peptide

Isoelectric Point

5.24pH

Molecular Weight

10.1kDa

Download CIF

Loading structure viewer...

Binding

Yes

Binding Strength

Medium

K_D

6.3×10⁻⁸M

k_on

4.5×10⁵M^-1s^-1

k_off

2.8×10⁻²s^-1

Download raw data

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

Loading kinetic curves...

Design Method

This protein was designed using GDAlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Parameters

backboneAlphaProteo

watermarkSynthIDBio-sequence, distortionary keys

temperature0.1

sequenceDesignProteinMPNN