TK(WL

Tadas Kluonis (Wells Wood Lab)

PhD student in Chris Wells Wood Lab

47proteins designed

3proteins validated

0binders

Collections created (1)

Submission 8

Tadas Kluonis (Wells Wood Lab) • about 2 months ago

Design methods created (1)

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

10 proteins generated

0 proteins tested

Design Methods Used

co-TIMED 33%

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement 67%

Protein Type

Miniprotein 15%

Nanobody 8%

Other 46%

Peptide 23%

scFv 8%

Binding Targets

EGFR 23%

Nipah Virus Glycoprotein G 77%

Proteins Designed (47)

TableGrid

TK(WLTadas Kluonis (Wells Wood Lab)

id: solid-gecko-willow

Binder

scFv

Target

Nipah Virus Glycoprotein G

0.77

79.26

25.8 kDa

244

TK(WLTadas Kluonis (Wells Wood Lab)

id: quick-goat-willow

Binder

Other

Target

Nipah Virus Glycoprotein G

0.84

84.07

20.7 kDa

181

TK(WLTadas Kluonis (Wells Wood Lab)

id: shy-toad-maple

Binder

Other

Target

Nipah Virus Glycoprotein G

0.81

77.75

16.0 kDa

138

TK(WLTadas Kluonis (Wells Wood Lab)

id: azure-cat-cypress

Binder

Nanobody

Target

Nipah Virus Glycoprotein G

0.83

91.00

13.1 kDa

119

TK(WLTadas Kluonis (Wells Wood Lab)

id: shy-bison-sand

Binder

Miniprotein

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

Target

Nipah Virus Glycoprotein G

0.81

86.44

7.0 kDa

TK(WLTadas Kluonis (Wells Wood Lab)

id: strong-tiger-thorn

Binder

Miniprotein

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

Target

Nipah Virus Glycoprotein G

0.76

68.23

6.8 kDa

TK(WLTadas Kluonis (Wells Wood Lab)

id: pale-bear-thorn

Binder

Other

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

Target

Nipah Virus Glycoprotein G

0.80

60.22

13.2 kDa

116

TK(WLTadas Kluonis (Wells Wood Lab)

id: wild-bear-maple

Binder

Other

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

Target

Nipah Virus Glycoprotein G

0.81

89.38

12.5 kDa

109

TK(WLTadas Kluonis (Wells Wood Lab)

id: crimson-falcon-orchid

Binder

Other

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

Target

Nipah Virus Glycoprotein G

0.84

89.07

10.7 kDa

TK(WLTadas Kluonis (Wells Wood Lab)

id: green-bear-cedar

Binder

Other

Stable, solluble miniproteins + Boltz2-ProteinMPNN refinement

Target

Nipah Virus Glycoprotein G

0.78

88.45

10.6 kDa

TK(WLTadas Kluonis (Wells Wood Lab)

id: amber-boar-snow

Binder

Peptide

co-TIMED

EGFR

None

83.83

True

5.2 kDa

TK(WLTadas Kluonis (Wells Wood Lab)

id: young-hawk-ash

Binder

Peptide

co-TIMED

EGFR

None

76.90

True

5.5 kDa

TK(WLTadas Kluonis (Wells Wood Lab)

id: bright-mole-frost

Binder

Peptide

co-TIMED

EGFR

None

82.35

True

5.4 kDa