Protein solid-hawk-stone

Nourelden Rihan / solid-hawk-stone

Type

Unknown

Ref

moPPIt_rank038

Collections

N[GEM x Adaptyv: RBX1 Binder Design Competition] Submission 1

AGEM x Adaptyv RBX1 Binder Competition: Main Submissions

Sequence (25 AA)

TYSEEYCKRKQDEDYGLYGRRGFLY

Computational Metrics

Experimental Metrics

Structure prediction unavailable

It might take a few hours to appear.

No experimental data

This protein hasn't been validated in the lab yet.

Design Method

This protein was designed using NRmoPPIt + PeptiVerse

Generation: 29 sequences, length 25 aa, targeting RBX1 hotspot motif (residues 18–36). Scoring: PeptiVerse API — binding affinity vs RBX1 (pKd), solubility, hemolysis, half-life at pH 7.4. Selection: all 29 sequences included. 14 tight-binding (pKd ≥ 9.0), 15 medium-binding (pKd 7–9). Best binder: pKd = 9.761.