Miniprotein rapid-tiger-fern

Type

Miniprotein

Binding

TREM2

Weak

Expressed

Yes

Ref

60_crow_RFDiffusion_ProteinMPNN_Boltz2

Collections

Sequence (84 AA)

SAEEILAAAAEHAERLAAFIAAASPEQARAIAAAVGASLRELGLEELGAAVEAAGAAATAATLPELGALAAEAVRRAAEAYAAA

Design Class

Miniprotein

Isoelectric Point

4.46pH

Molecular Weight

8080.94Da

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Binding

Yes

Binding Strength

Weak

1.2e-6M

Kon

7.6e+4M-1s-1

Koff

8.8e-2s-1

Kinetic Curves (SPR)

Concentration

100 nM

316 nM

1000 nM

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This protein was designed using BLRFdiffusion

RFDiffusion + ProteinMPNN + Boltz2