Miniprotein mellow-bee-ash

Type

Miniprotein

Binding

TREM2

Weak

Expressed

Yes

Ref

53_crow_RFDiffusion_ProteinMPNN_Boltz2

Collections

Sequence (84 AA)

SAEAVIAAAREHAARLAAFIAASSVADAKKIAAAIGESLREAGLEDLGAQVTAAGAAMTAATKAALGALAAAAVVAAAEAVAAA

Design Class

Miniprotein

Isoelectric Point

5.16pH

Molecular Weight

7783.79Da

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Binding

Yes

Binding Strength

Weak, Medium

9.5e-7M

Kon

1.2e+5M-1s-1

Koff

1.1e-1s-1

Kinetic Curves (SPR)

Concentration

316 nM

1000 nM

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This protein was designed using BLRFdiffusion

RFDiffusion + ProteinMPNN + Boltz2