Miniprotein amber-swan-opal

Type

Miniprotein

Binding

TREM2

Medium

Expressed

Yes

Ref

6_NovoFy_RFDiffusion_LigandMPNN_Boltz

Collections

Sequence (90 AA)

LDAVLAALRARLAAWADRLAAAGDVAGAVAWLRAVADDLDALGTPECRAAAAEFRAEAAALEASGRFTAAQLRAAADRAAAVLEAALRAA

Design Class

Miniprotein

Isoelectric Point

4.96pH

Molecular Weight

9027.13Da

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Binding

Yes

Binding Strength

Medium

7.1e-7M

Kon

2.8e+5M-1s-1

Koff

1.8e-1s-1

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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This protein was designed using BLRFdiffusion

RFDiffusion + LigandMPNN + Boltz