BindCraft is a computationally expensive process. Some trajectories passed initial stage with high iptm scores but were rejected from the filter after MPNN optimisation. We attempted to use Soluble Caliby, a Potts model based sequence design method, (Shuai et al., 2025) to rescue those designs. Interface residues predicted by BindCraft was fixed. Collab effort from Gabriel Ong and Honghao Su.
id: golden-jaguar-thorn

Nipah Virus Glycoprotein G
0.79
83.02
--
16.8 kDa
144
id: jade-cobra-pearl

Nipah Virus Glycoprotein G
0.79
82.64
--
18.8 kDa
150
id: young-toad-ice

Nipah Virus Glycoprotein G
0.76
75.75
--
13.7 kDa
113
id: ivory-zebra-ash

Nipah Virus Glycoprotein G
0.76
75.52
--
13.7 kDa
113
id: deep-quail-crystal

Nipah Virus Glycoprotein G
0.75
84.04
--
9.0 kDa
77