4 designs were designed using de novo peptide scaffolding using RFdiffusion + additional partial diffusion rounds. 3 designs were designed using protein hunter + additional ProteinMPNN rounds.
All designs were scored using AF3 + Boltz2 ipSAE_min and ipSAE_max.
id: hollow-ibis-jade
Nipah Virus Glycoprotein G
0.84
84.11
--
14.7 kDa
128
id: young-mole-frost
Nipah Virus Glycoprotein G
0.79
72.91
--
11.2 kDa
104
id: wild-bee-orchid
Nipah Virus Glycoprotein G
0.79
88.04
--
14.3 kDa
128
id: strong-swan-cypress
Nipah Virus Glycoprotein G
0.78
77.55
--
14.2 kDa
128
id: scarlet-orca-oak
Nipah Virus Glycoprotein G
0.77
77.33
--
11.6 kDa
104
id: silent-ram-quartz
Nipah Virus Glycoprotein G
0.77
73.88
--
11.0 kDa
104
id: quiet-lynx-cloud
Nipah Virus Glycoprotein G
0.75
74.94
--
11.1 kDa
104