4 designs were designed using de novo peptide scaffolding using RFdiffusion + additional partial diffusion rounds. 3 designs were designed using protein hunter + additional ProteinMPNN rounds.
All designs were scored using AF3 + Boltz2 ipSAE_min and ipSAE_max.
id: wild-bee-orchid
Multiple (2)
Medium (6)
True
14.3 kDa
128
id: hollow-ibis-jade
Nipah Virus Glycoprotein G
None
84.11
True
14.7 kDa
128
id: strong-swan-cypress
Nipah Virus Glycoprotein G
None
80.07
True
14.2 kDa
128
id: quiet-lynx-cloud
Nipah Virus Glycoprotein G
None
74.94
False
11.1 kDa
104
id: young-mole-frost
Nipah Virus Glycoprotein G
None
72.91
True
11.2 kDa
104
id: scarlet-orca-oak
Nipah Virus Glycoprotein G
None
73.32
True
11.6 kDa
104
id: silent-ram-quartz
Nipah Virus Glycoprotein G
None
73.88
False
11.0 kDa
104