Submission 1 | Proteinbase

Proteins
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Targets
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Submission 1 | Proteinbase

A

Andy Lau/Submission 1

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Submitted toNipah Binder Competition

Description

BoltzGen to generate backbones and internal InstaDeep pipeline to optimise sequences

About

9proteins designed

9proteins validated

1binders

89%expression rate

0.79Avg ipSAE

Design Methods

Targets

Nipah Virus Glycoprotein G

1 binder•1.3e-7 avg KD

Human Serum Albumin

0 binders•-- avg KD

Design Class

other 89%

miniprotein 11%

Binding Strength

none 89%

medium 11%

Expressed

true 89%

unknown 11%

De Novo

yes 89%

unknown 11%

Classification

mainly Alpha 100%

Architecture

unknown 100%

Proteins (9)

TableGrid

id: frozen-gecko-leaf

Binder

Other

BoltzGen

frozen-gecko-leaf

Multiple (2)

Medium (3)

True

10.6 kDa

95

id: bright-lynx-ruby

Binder

Other

BoltzGen

bright-lynx-ruby

Nipah Virus Glycoprotein G

None

87.38

True

11.2 kDa

96

id: silent-panther-ruby

Binder

Other

BoltzGen

silent-panther-ruby

Nipah Virus Glycoprotein G

None

88.39

True

10.9 kDa

98

id: silent-otter-jade

Binder

Other

BoltzGen

silent-otter-jade

Nipah Virus Glycoprotein G

None

88.01

True

11.3 kDa

98

id: rough-jaguar-birch

Binder

Other

BoltzGen

rough-jaguar-birch

Nipah Virus Glycoprotein G

None

88.45

True

10.9 kDa

95

id: soft-yak-oak

Binder

Miniprotein

BoltzGen

soft-yak-oak

Nipah Virus Glycoprotein G

None

91.40

True

10.1 kDa

95

id: vast-mole-orchid

Binder

Other

BoltzGen

vast-mole-orchid

Nipah Virus Glycoprotein G

None

87.18

True

11.4 kDa

98

id: brisk-fox-clay

Binder

Other

BoltzGen

brisk-fox-clay

Nipah Virus Glycoprotein G

None

87.87

True

11.1 kDa

98

id: silent-raven-frost

Binder

Other

BoltzGen

silent-raven-frost

Nipah Virus Glycoprotein G

0.82

87.49

--

11.3 kDa

96

Rows per page

1-9 of 9