SARS-CoV-2 RBD

270 proteins validated

228 binders

Average K_D: 2.4×10⁻⁷ M

Sequence (219 AA)

RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNK

Proteins targeting SARS-CoV-2 RBD (270)

TableGrid

GDGoogle DeepMind

id: vast-jaguar-pine

Binder

Peptide

AlphaProteo (parent sequence)

Target

SARS-CoV-2 RBD

Binding

Strong

2.4e-9 M

True

9.9 kDa

101

id: quiet-owl-bronze

Binder

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

2.8e-9 M

True

12.3 kDa

109

id: calm-kiwi-reed

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (non-distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

4.1e-9 M

True

8.9 kDa

id: green-ox-cedar

Binder

AlphaProteo (parent sequence)

Target

SARS-CoV-2 RBD

Binding

Strong

8.7e-9 M

True

12.7 kDa

123

id: small-gecko-granite

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.1e-8 M

True

9.6 kDa

id: crimson-tiger-ember

Binder

Peptide

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.2e-8 M

True

9.9 kDa

101

id: small-kiwi-maple

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Strong

1.4e-8 M

True

8.9 kDa

id: jade-falcon-sand

Binder

Peptide

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Strong

1.5e-8 M

True

9.8 kDa

101

id: green-seal-clay

Binder

Peptide

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.6e-8 M

True

10.1 kDa

101

id: crimson-fox-ice

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.6e-8 M

True

9.4 kDa

id: golden-heron-topaz

Binder

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.6e-8 M

True

12.2 kDa

120

id: rough-ant-quartz

Binder

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Strong

1.7e-8 M

True

12.7 kDa

123

id: frozen-kiwi-sand

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.7e-8 M

True

9.5 kDa

id: shy-boar-moss

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

1.9e-8 M

True

9.5 kDa

id: violet-heron-ivy

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Strong

1.9e-8 M

True

7.1 kDa

id: silent-ant-topaz

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Strong

2.0e-8 M

True

8.9 kDa

id: calm-bat-orchid

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

2.0e-8 M

True

9.4 kDa

id: bright-seal-cloud

Binder

Miniprotein

AlphaProteo (parent sequence)

Target

SARS-CoV-2 RBD

Binding

Strong

2.1e-8 M

True

9.8 kDa

100

id: soft-raven-oak

Binder

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

2.1e-8 M

True

12.4 kDa

120

id: green-bear-marble

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN (no watermark)

Target

SARS-CoV-2 RBD

Binding

Strong

2.2e-8 M

True

8.8 kDa

id: hollow-falcon-marble

Binder

Miniprotein

AlphaProteo backbone + ProteinMPNN with SynthIDBio (distortionary)

Target

SARS-CoV-2 RBD

Binding

Strong

2.2e-8 M

Expressed

True

Mol. Weight

7.4 kDa

AA Length

SARS-CoV-2 RBD

Proteins targeting SARS-CoV-2 RBD (270)

Proteins targeting SARS-CoV-2 RBD (…)

Proteins targeting SARS-CoV-2 RBD (270)