Miniprotein solid-toad-topaz | Proteinbase

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Design Methods
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Created by

Miniprotein solid-toad-topaz | Proteinbase

ET

Elise Therond / solid-toad-topaz

Type

Miniprotein

Binding

Myostatin (GDF-8)

None

Expressed

Yes

Ref

Final_rank9,

Collections

AGDF-8 Challenge Results

Sequence (44 AA)

AAAAAAAAARAAQAAQAAAIVARAEETQRKLELNELLEKLRALK

Sequence (44 AA)

AAAAAAAAARAAQAAQAAAIVARAEETQRKLELNELLEKLRALK

Computational Metrics

Experimental Metrics

Design Class

Miniprotein

Isoelectric Point

9.69pH

Molecular Weight

4.5kDa

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Binding

No

Binding Strength

None

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Design Method

This protein was designed using ETBart Roest approach : RFDiffusion3 + LigandPNN + ESM2 + AlphaFold + Selection

Proteins
solid-toad-topaz

Download raw data

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM