Miniprotein scarlet-toad-opal

Type

Miniprotein

Binding

TNF-α

Strong

Expressed

Yes

Ref

TNFA_UNOPT_01

Collections

Sequence (138 AA)

QAADLATLLAAADAVHARFAALLAAAAERPLSDAEVEALVAEVRAILTAAIEALTSLDPETRAFLLGRLDRALAGVLAELRLAAKSEDPEERAEALLDAAARVAHFLEDVAAHALDPADLAALRARLAAQLAALRALA

Design Class

Miniprotein

Isoelectric Point

4.71pH

Molecular Weight

14.2kDa

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Binding

Yes

Binding Strength

Strong

K_D

6.6×10⁻⁹M

k_on (1:1)

8.4×10⁴M^-1s^-1

k_off (1:1)

5.8×10⁻⁴s^-1

Kinetic Curves (BLI)

Fit Model

Concentration

0.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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