Unknown
rbx1_gen_0010|helix_v1_A2R,R7I,L12W,A14G|iPTM=0.846|pLDDT=0.818|composite=0.6925
Sequence (14 AA)
ERRQDLIMDASWRG
Structure prediction unavailable
It might take a few hours to appear.
No experimental data
This protein hasn't been validated in the lab yet.
This protein was designed using BCSAE-Steered ESM2 + Topological Pre-Filtering + Boltz-2
Base model: facebook/esm2_t33_650M_UR50D (650M params, MPS-accelerated) SAE: InterPLM esm2-650m layer 18 (HuggingFace: Elana/InterPLM-esm2-650m) Steering feature: f5922 (helix), clamp=10.0 Topo filter: PH-entropy <= 1.1841 (linear), computed via ripser on Vietoris-Rips filtration Variants per parent: 5 (4 mutations each, temperature=1.0) Boltz-2 for structure prediction Target: RBX-1 RING domain residues 40-108, PDB 1LDK